Platelet monoamine oxidase activity and headache.

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Platelet monoamine oxidase activity and headache.

Mean platelet monoamine oxidase activity was reduced compared with control values in groups of headache-free male (but not female) patients suffering from classical migraine and from tension headache. Mean activity in male cluster patients, headache free, both during acute and quiescent phases of their illness, was also notably reduced. Retesting some migraine subjects after up to four years, s...

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Platelet monoamine oxidase activity in megaloblastic anaemia.

Platelet monoamine oxidase activity has been measured in 17 patients with megaloblastic anaemia due to either vitamin B12 or folate deficiency, and in 20 healthy subjects. There was a highly significant increase in patients compared with controls. In two patients, platelet activity decreased following successful treatment. A significant correlation between platelet activity and the severity of ...

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Platelet monoamine oxidase activity in Huntington's chorea.

The possibility that genetically determined abnormalities in the monoamine oxidase of certain central nervous system aminergic neurones may play a part in the pathology of Huntington's chorea was investigated using human platelet monoamine oxidase. Significantly elevated monoamine oxidase activity was found in male patients compared to control subjects suggesting this may be a screening test fo...

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Platelet monoamine oxidase activity in diabetics.

Plateiet monoamine ox!dase (MAO) activity was determined, using benzylainine as substract. Results are expressed as nM benzaidehyde/nig protein hour, at 37. A total of 79 diabetics (40 M and 39 F) ranging in age from 3 to 70 years was stud,ed. A normal control group inciuded 39 persons (17 M and 22 F) ranging in age from 16 to 60 years. Piatelet MAO activity shows a slight variation in relation...

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Human platelet monoamine oxidase activity in glaucoma.

Monoamine oxidase (MAO, E.C. 1.4.3.4) activity was determined by spectrophotofluorimetric assay of the reaction product of the artificial substrate kynuramine in platelets from venous blood samples from 50 outpatients with glaucomas and 47 sex- and age-matched controls. No significant differences were found between MAO activity in control subjects and that in subjects with glaucomas grouped acc...

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ژورنال

عنوان ژورنال: Journal of Neurology, Neurosurgery & Psychiatry

سال: 1981

ISSN: 0022-3050

DOI: 10.1136/jnnp.44.9.786